HOUSE: L-R: Robert Sean Leonard, Olivia Wilde, Jesse Spencer, Kal Penn, Hugh Laurie, Omar Epps, Lisa Edelstein, Jennifer Morrisson, Peter Jacobson. The fifth season of HOUSE premieres Tuesday, Sept. 16 (8:00-9:00 PM ET/PT) on FOX. ©2008 Fox Broadcasting Co. Cr: Timothy White/FOX

HOUSE: Hugh Laurie as Dr. Gregory House. The fifth season of HOUSE premieres Tuesday, Sept. 16 (8:00-9:00 PM ET/PT) on FOX. ©2008 Fox Broadcasting Co. Cr: Timothy White/FOX

HOUSE: Hugh Laurie as Dr. Gregory House. The fifth season of HOUSE premieres Tuesday, Sept. 16 (8:00-9:00 PM ET/PT) on FOX. ©2008 Fox Broadcasting Co. Cr: Timothy White/FOX

HOUSE: Jennifer Morrison as Dr. Allison Cameron. The fifth season of HOUSE premieres Tuesday, Sept. 16 (8:00-9:00 PM ET/PT) on FOX. ©2008 Fox Broadcasting Co. Cr: Joseph Viles/FOX

HOUSE: Jesse Spencer as Dr. Robert Chase. The fifth season of HOUSE premieres Tuesday, Sept. 16 (8:00-9:00 PM ET/PT) on FOX. ©2008 Fox Broadcasting Co. Cr: Joseph Viles/FOX

HOUSE: Kal Penn as Dr. Lawrence Kutner. The fifth season of HOUSE premieres Tuesday, Sept. 16 (8:00-9:00 PM ET/PT) on FOX. ©2008 Fox Broadcasting Co. Cr: Joseph Viles/FOX

HOUSE: Lisa Edelstein as Dr. Lisa Cuddy. The fifth season of HOUSE premieres Tuesday, Sept. 16 (8:00-9:00 PM ET/PT) on FOX. ©2008 Fox Broadcasting Co. Cr: Joseph Viles/FOX

HOUSE: Olivia Wilde as Dr. Remy Hadley. The fifth season of HOUSE premieres Tuesday, Sept. 16 (8:00-9:00 PM ET/PT) on FOX. ©2008 Fox Broadcasting Co. Cr: Joseph Viles/FOX

HOUSE: Omar Epps as Dr. Eric Foreman. The fifth season of HOUSE premieres Tuesday, Sept. 16 (8:00-9:00 PM ET/PT) on FOX. ©2008 Fox Broadcasting Co. Cr: Joseph Viles/FOX

HOUSE: Peter Jacobson as Dr. Chris Taub. The fifth season of HOUSE premieres Tuesday, Sept. 16 (8:00-9:00 PM ET/PT) on FOX. ©2008 Fox Broadcasting Co. Cr: Joseph Viles/FOX

HOUSE: Robert Sean Leonard as Dr. James Wilson. The fifth season of HOUSE premieres Tuesday, Sept. 16 (8:00-9:00 PM ET/PT) on FOX. ©2008 Fox Broadcasting Co. Cr: Joseph Viles/FOX